Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817779 | 0.92 | MAPT (0.43) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6818033 | 0.88 | MAPT (0.43) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL7065294 | 0.88 | CRHR1 (0.46) | PIK3CAPIK3CBPIK3CGSMN1; SMN2HTT | |
| SCHEMBL6818822 | 0.84 | MAPT (0.39) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6817889 | 0.83 | MAPT (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6814158 | 0.83 | ALDH1A1 (0.33) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6814129 | 0.82 | PRKCQ (0.38) | MEN1KMT2APIK3CAPIK3CBPIK3CG | |
| SCHEMBL6818521 | 0.82 | MAPT (0.44) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6817723 | 0.82 | CRHR1 (0.38) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6817813 | 0.81 | PRKCQ (0.39) | MEN1KMT2APIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004031189-A1 | PYRIDINO AND PYRIMIDINO PYRAZINONES FOR TREATMENT OF ANXIETY AND DEPRESSION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |