Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIEZO1 | Q92508 | 2/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 5/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823195 | 0.76 | PIEZO1 (0.44) | PIEZO1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL6819312 | 0.76 | PIEZO1 (0.44) | PIEZO1ALDH1A1KMT2AMAPTSLC6A2 | |
| SCHEMBL6820091 | 0.75 | NOTUM (0.40) | — | |
| SCHEMBL6074928 | 0.73 | RAB9A (0.48) | PIEZO1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL6822871 | 0.71 | IDO1 (0.32) | KMT2AMAPTSLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL6818762 | 0.71 | NOS3 (0.40) | ALDH1A1TSHRKMT2AMAPTSLC6A2 | |
| SCHEMBL5406690 | 0.70 | NOTUM (0.41) | PIEZO1CYP2D6NPC1RAB9AKDM4E | |
| SCHEMBL5605178 | 0.70 | IDO1 (0.53) | ALDH1A1TSHRKMT2ACYP2D6KDM4E | |
| SCHEMBL6816069 | 0.69 | ENPP2 (0.35) | KMT2AMAPTSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL27604626 | 0.69 | RAB9A (0.42) | PIEZO1ALDH1A1TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |