Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819839 | 1.00 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1F10F2 | |
| SCHEMBL6819770 | 0.84 | MMP2 (0.44) | MMP2MMP3ALDH1A1 | |
| SCHEMBL6818664 | 0.84 | HDAC3 (0.45) | F10F2MMP2MMP3ALDH1A1 | |
| SCHEMBL6819772 | 0.84 | MMP2 (0.44) | MMP2MMP3ALDH1A1 | |
| SCHEMBL1329533 | 0.82 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1F10MMP2 | |
| SCHEMBL29417563 | 0.81 | MME (0.48) | SLC1A3SLC1A2SLC1A1F10F2 | |
| SCHEMBL6818217 | 0.80 | ITGB3 (0.41) | SLC1A3SLC1A2SLC1A1F2MMP2 | |
| SCHEMBL16938448 | 0.77 | CA2 (0.48) | SLC1A3SLC1A2SLC1A1F10F2 | |
| SCHEMBL6819150 | 0.76 | CTSL (0.43) | SLC1A3SLC1A2SLC1A1F10MMP2 | |
| SCHEMBL6818927 | 0.76 | CTSL (0.43) | SLC1A3SLC1A2SLC1A1F10MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |