SCHEMBL6820313

SCHEMBL6820313

O=S(=O)(c1ccccc1)n1ccnn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.42
MET P08581 1/20 0.42
SLC9A1 P19634 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HTR6 P50406 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
CYP2C9 P11712 2/20 0.40
MMP2 P08253 1/20 0.40
PARL Q9H300 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP19A1 P11511 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1976805 0.81 CA1 (0.50) SLC9A1ALDH1A1MEN1KMT2ALMNA
SCHEMBL5396539 0.80 GRM4 (0.44) ALDH1A1HTR6MEN1KMT2ALMNA
SCHEMBL3734126 0.78 PARL (0.47) ALDH1A1MEN1KMT2ALMNAHPGD
SCHEMBL4254051 0.74 POLB (0.54) CYP2C19METSLC9A1ALDH1A1HTR6
SCHEMBL8712666 0.73 NOTUM (0.42) CYP2C19SLC9A1ALDH1A1HTR6MEN1
SCHEMBL29414534 0.73 CYP19A1 (0.47) CYP2C19ALDH1A1MEN1KMT2AHPGD
SCHEMBL7368521 0.72 ALDH1A1 (0.40) CYP2C19METSLC9A1ALDH1A1HTR6
SCHEMBL29589411 0.69 PARL (0.46) ALDH1A1HTR6MEN1KMT2AHPGD
SCHEMBL2762763 0.68 ALDH1A1 (0.66) ALDH1A1HTR6KMT2ALMNATSHR
SCHEMBL4252110 0.68 ALDH1A1 (0.47) CYP2C19METSLC9A1ALDH1A1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129031-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD (IN) 2025-04-24 US disclosed
US-6673747-B2 FOR CONTROLLING OF UNDESIRED PLANT GROWTH IN CROPS OF CULTIVATED PLANTS SYNGENTA PARTICIPATIONS AG (CH) 2004-01-06 US disclosed
US-20020193253-A1 Herbicidal composition KRUGER CHRISTIAN (DE) 2002-12-19 US disclosed
US-20020045549-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-04-18 US disclosed
EP-1126758-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2001-08-29 EP disclosed
WO-2000025586-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2000-05-11 WO disclosed
EP-0605230-A1 Hexanhydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO COMPANY LIMITED (JP) 1994-07-06 EP disclosed
US-4474947-A Benzazolides and their employment in phosphate ester oligonucleotide synthesis processes BIOSEARCH (US) 1984-10-02 US disclosed
US-4426517-A Process for de-cyanoethylating blocked nucleotides ELI LILLY AND COMPANY (US) 1984-01-17 US disclosed
US-4419509-A Process for de-cyanoethylating blocked nucleotides ELI LILLY AND COMPANY (US) 1983-12-06 US disclosed
US-4417046-A Process for isolating oligonucleotide product from a coupling reaction mixture ELI LILLY AND COMPANY (US) 1983-11-22 US disclosed
EP-0075392-A1 Process for de-cyanoethylating blocked nucleotides ELI LILLY AND COMPANY (US) 1983-03-30 EP disclosed
EP-0002322-A2 Improved Triester process for the synthesis of oligonucleotides GENENTECH, INC. (US) 1979-06-13 EP disclosed
US-3963731-A TREATMENT OF GOUT AND HYPERURICEMIA MERCK & CO., INC. (US) 1976-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193253-A1 Herbicidal composition DDT, DPP4, DPP7 CYP2C19 695/4885MET 478/4885SLC9A1 1979/4885
US-20250129031-A1 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF GLP1R, CBR3, CBR1 CYP2C19 1085/4885MET 4207/4885SLC9A1 725/4885
US-20020045549-A1 Herbicidal composition DDT, DPP4, DPP7 CYP2C19 695/4885MET 478/4885SLC9A1 1979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.