Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881482 | 0.81 | MAPT (0.47) | SLC9A1LMNAALDH1A1MMP2CXCL8 | |
| SCHEMBL5694032 | 0.75 | GAA (0.42) | NOTUMALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6820313 | 0.73 | CYP2C19 (0.42) | SLC9A1LMNACYP2C9ALDH1A1CYP2D6 | |
| SCHEMBL11073965 | 0.69 | CYP19A1 (0.43) | SLC9A1CYP2C9ALDH1A1CYP2D6MMP2 | |
| SCHEMBL4254051 | 0.67 | POLB (0.54) | SLC9A1LMNACYP2C9ALDH1A1CYP2D6 | |
| SCHEMBL5694221 | 0.66 | RAPGEF4 (0.45) | NOTUMALDH1A1MMP2TDP1PIK3CD | |
| SCHEMBL16050475 | 0.65 | HTR6 (0.43) | SLC9A1LMNACYP2C9ALDH1A1CYP2D6 | |
| SCHEMBL2762763 | 0.64 | ALDH1A1 (0.66) | LMNAALDH1A1HSD17B10HTR6L3MBTL1 | |
| Dimethyl Sulfone SCHEMBL20720495 | 0.64 | NOTUM (0.78) | NOTUMLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL7368521 | 0.64 | ALDH1A1 (0.40) | SLC9A1LMNACYP2C9ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059592-A | COUPLING AGENTS | CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) | 1977-11-22 | — | — | US | claimed |
| EP-0639582-B1 | Polynucleotide assay reagent and method | ANTIVIRALS INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0215942-B1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | ANTIVIRALS INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0639582-A2 | Polynucleotide assay reagent and method | ANTIVIRALS INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0215942-A4 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1988-08-23 | — | — | EP | disclosed |
| EP-0215942-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. | SUMMERTON JAMES | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005519-A1 | POLYNUCLEOTIDE ASSAY REAGENT AND METHOD | SUMMERTON JAMES | 1986-09-25 | — | — | WO | disclosed |
| US-4059592-A | COUPLING AGENTS | CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) | 1977-11-22 | — | — | US | disclosed |