Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976805 | 0.78 | CA1 (0.50) | LMNASMN1; SMN2MEN1PKMKMT2A | |
| SCHEMBL6820313 | 0.78 | CYP2C19 (0.42) | PARLLMNASMN1; SMN2MEN1HPGD | |
| SCHEMBL11286964 | 0.76 | ALDH1A1 (0.42) | LMNASMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL29588103 | 0.74 | ALDH1A1 (0.41) | PARLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1260021 | 0.71 | NOTUM (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31024013 | 0.71 | TP53 (0.59) | PARLKMT2ACA1CA2CA12 | |
| SCHEMBL1096992 | 0.71 | PARL (0.47) | PARLLMNASMN1; SMN2MEN1PKM | |
| SCHEMBL15315388 | 0.70 | CA2 (0.58) | PARLLMNASMN1; SMN2CA1CA2 | |
| SCHEMBL1519692 | 0.68 | ALDH1A1 (0.69) | PARLLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3141993 | 0.68 | CYP19A1 (0.57) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022215745-A1 | SUBSTANCE OF NOVEL SIDEROPHORE-TYPE ANTIFUNGAL AGENT (COMPOUND) AND USE OF SAME | 国立研究開発法人理化学研究所 | 2022-10-13 | — | — | WO | disclosed |
| US-7829580-B2 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090233366-A1 | COMPOSITION FOR INTRODUCTION OF NUCLEIC ACID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2080767-A1 | COMPOSITION FOR INTRODUCTION OF NUCLEIC ACID | Daiichi Sankyo Company, Limited (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-20090022782-A1 | Blood Retainable Device Exhibiting Selective Degradability in Tumor Tissue | NATIONAL UNIVERSITY CORP. HOKKAIDO UNIVERSITY (JP) | 2009-01-22 | — | — | US | disclosed |
| US-7396930-B2 | making spiro(benzo(c)thiophene-1 (3H),4'-piperidine) derivatives; involves reacting a mercapto compound with a 2-halophenylalkyl halide, reacting with an alkyllithium, then N-ethoxycarbonyl-4-piperidone, dehydration and cyclization; industrial scale; novel intermediates to neurokinin receptor antagonist | SANKYO COMPANY, LIMITED (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-1889835-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2008-02-20 | — | — | EP | disclosed |
| EP-1862470-A1 | ELEMENT RETAINED IN BLOOD SHOWING DEGRADABILITY SELECTIVELY IN TUMOR TISSUE | National University Corporation Hokkaido University (JP) | 2007-12-05 | — | — | EP | disclosed |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5451688-A | Inhibit biosynthesis of cholesterol | SANKYO COMPANY, LIMITED (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-4474947-A | Benzazolides and their employment in phosphate ester oligonucleotide synthesis processes | BIOSEARCH (US) | 1984-10-02 | — | — | US | disclosed |
| US-4426517-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| US-4419509-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| US-4417046-A | Process for isolating oligonucleotide product from a coupling reaction mixture | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0075392-A1 | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-03-30 | — | — | EP | disclosed |
| EP-0002322-A2 | Improved Triester process for the synthesis of oligonucleotides | GENENTECH, INC. (US) | 1979-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | MPI, ITPA, DCPS | PARL 3246/4885LMNA 4484/4885SMN1; SMN2 4697/4885 |
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | CBR3, CNR1, C3AR1 | PARL 2785/4885LMNA 1421/4885SMN1; SMN2 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.