Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820565 | 0.84 | KCNA3 (0.36) | STK17BKCNA3MTNR1APNLIPMAOA | |
| SCHEMBL6422310 | 0.84 | MTNR1A (0.36) | STK17BKCNA3MTNR1ATDP1PNLIP | |
| SCHEMBL6823692 | 0.83 | STK17B (0.31) | STK17B | |
| SCHEMBL6426238 | 0.83 | KCNA3 (0.37) | STK17BKCNA3MTNR1APNLIPMAOA | |
| SCHEMBL6823437 | 0.81 | TSHR (0.41) | KCNA3MTNR1A | |
| SCHEMBL6824170 | 0.79 | LMNA (0.47) | STK17BKCNA3MTNR1APRKCA | |
| SCHEMBL6826208 | 0.77 | F2RL3 (0.41) | STK17BTDP1PRKCA | |
| SCHEMBL6421954 | 0.74 | ALDH1A1 (0.41) | TDP1 | |
| SCHEMBL6823335 | 0.73 | KCNA3 (0.33) | KCNA3TDP1PRKCA | |
| SCHEMBL6826721 | 0.73 | MEN1 (0.45) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |