SCHEMBL6823692

SCHEMBL6823692

CC(C)=C1Oc2cccc(OC(C)CCC(C)Br)c2C1=O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
STK17B O94768 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6824139 0.73 CA1 (0.34) CA1CA2CA7CA9
SCHEMBL6820565 0.72 KCNA3 (0.36) STK17B
SCHEMBL6426238 0.70 KCNA3 (0.37) STK17B
SCHEMBL6824170 0.69 LMNA (0.47) STK17B
SCHEMBL6421978 0.67 TYR (0.49)
SCHEMBL7347199 0.67 MAOB (0.33) STK17B
SCHEMBL7346833 0.66 MAOB (0.37) STK17B
SCHEMBL7346994 0.65 TXNRD1 (0.34) STK17B
SCHEMBL6826721 0.62 MEN1 (0.45)
SCHEMBL6826161 0.60 MTNR1A (0.35) STK17B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076444-A2 NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC F. HOFFMANN-LA ROCHE AG (CH) 2004-09-10 WO disclosed