Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437607 | 0.80 | PTGS2 (0.48) | L3MBTL1KMT2AALDH1A1BACE1PTGS2 | |
| SCHEMBL30534775 | 0.80 | PTGS2 (0.48) | L3MBTL1KMT2AALDH1A1BACE1PTGS2 | |
| SCHEMBL27540149 | 0.75 | HTR1B (0.44) | HPGDSMN1; SMN2KMT2AALDH1A1TP53 | |
| SCHEMBL6820709 | 0.74 | L3MBTL1 (0.54) | L3MBTL1KMT2AALDH1A1BACE1MTNR1A | |
| Indole SCHEMBL8436345 | 0.74 | ESR1 (0.42) | L3MBTL1KMT2AALDH1A1PTGS2 | |
| SCHEMBL11558486 | 0.73 | ALDH1A1 (0.65) | L3MBTL1HPGDSMN1; SMN2KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11555475 | 0.72 | ALDH1A1 (0.63) | L3MBTL1HPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5075270 | 0.72 | PTGS2 (0.53) | L3MBTL1SMN1; SMN2KMT2AALDH1A1MTNR1A | |
| SCHEMBL4887683 | 0.72 | L3MBTL1 (0.61) | L3MBTL1SMN1; SMN2KMT2AALDH1A1MTNR1A | |
| SCHEMBL11689282 | 0.71 | ALDH1A1 (0.61) | L3MBTL1KMT2AALDH1A1BACE1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010021719-A1 | 2-phenyl-1- [4- (2-aminoethoxy) - benzyl] - indoles as estrogenic agents | WYETH | 2001-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021719-A1 | 2-phenyl-1- [4- (2-aminoethoxy) - benzyl] - indoles as estrogenic agents | ESR1, ESR2, GPER1 | L3MBTL1 4671/4885HPGD 177/4885SMN1; SMN2 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.