Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466369 | 0.80 | TYMP (0.41) | ALDH1A1HPGDKDM4EKMT2ADAO | |
| SCHEMBL2943501 | 0.79 | LTB4R (0.62) | LTB4RALDH1A1HPGDGAAKDM4E | |
| Hydrochloric Acid SCHEMBL28305301 | 0.77 | LTB4R (0.61) | LTB4RALDH1A1HPGDGAAKDM4E | |
| SCHEMBL15515881 | 0.77 | LTB4R (0.47) | LTB4RALDH1A1HPGDGAAKDM4E | |
| SCHEMBL28647090 | 0.75 | LTB4R (0.49) | LTB4RALDH1A1HPGDGAAKDM4E | |
| SCHEMBL6600284 | 0.74 | LMNA (0.45) | LTB4RALDH1A1HPGDGAAKDM4E | |
| SCHEMBL11116236 | 0.73 | LTB4R (0.44) | LTB4RALDH1A1GAAHSD17B10KMT2A | |
| SCHEMBL27653924 | 0.72 | KDM4E (0.58) | ALDH1A1HPGDKDM4EHSD17B10PARP1 | |
| SCHEMBL11121501 | 0.70 | LTB4R (0.51) | LTB4RALDH1A1HPGDGAAKDM4E | |
| SCHEMBL6601040 | 0.69 | ALDH1A1 (0.51) | LTB4RALDH1A1GAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020512-A9 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2004-05-06 | — | — | WO | disclosed |
| EP-1351958-A1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | AstraZeneca AB (SE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002020512-A1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |