Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918963 | 0.84 | KDR (0.50) | CA12CA2CA9SRCAKR1B10 | |
| SCHEMBL6821059 | 0.83 | MAPT (0.48) | SRCAKR1B10AKR1A1AKR1B1HDAC1 | |
| SCHEMBL3855156 | 0.83 | GRIK2 (0.50) | PLA2G2ANPC1CFTRMAPK8KMT2A | |
| SCHEMBL6821169 | 0.83 | KMT2A (0.52) | PLA2G2ASRCMAPK8KMT2AMEN1 | |
| SCHEMBL3853087 | 0.82 | PLA2G2A (0.49) | CA12CA2CA9PLA2G2ANPC1 | |
| SCHEMBL6820233 | 0.82 | CYP19A1 (0.59) | SRCHDAC1HDAC6KMT2AMEN1 | |
| SCHEMBL6821095 | 0.82 | PLA2G2A (0.60) | CA12CA2CA9PLA2G2ANPC1 | |
| SCHEMBL2244878 | 0.80 | CYP19A1 (0.60) | CA12CA2CA9PLA2G2ANPC1 | |
| SCHEMBL31222301 | 0.80 | CYP19A1 (0.60) | CA12CA2CA9PLA2G2ANPC1 | |
| SCHEMBL6821058 | 0.80 | PLA2G2A (0.57) | PLA2G2AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |