Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919706 | 0.81 | CYP2C9 (0.45) | CXCR3GRM5CYP2C9CYP2C19MAPT | |
| SCHEMBL6825456 | 0.77 | CXCR3 (0.43) | CXCR3GRM5CYP2C9CYP2C19MAPT | |
| SCHEMBL7190383 | 0.76 | CXCR3 (0.42) | CXCR3GRM5CYP2C9CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL6821246 | 0.74 | CYP2C9 (0.46) | CXCR3GRM5CYP2C9CYP2C19MAPT | |
| SCHEMBL6919652 | 0.67 | P2RY12 (0.45) | CXCR3GRM5KDM4EMEN1KMT2A | |
| SCHEMBL13648884 | 0.67 | CXCR3 (0.55) | CXCR3 | |
| SCHEMBL6826032 | 0.66 | P2RY12 (0.49) | CXCR3GRM5HPGDP2RY12 | |
| Hydrochloric Acid SCHEMBL3976856 | 0.66 | CXCR3 (0.54) | CXCR3 | |
| Hydrochloric Acid SCHEMBL6921349 | 0.66 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGD | |
| SCHEMBL7196412 | 0.65 | MEN1 (0.56) | CXCR3MAPTKDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074278-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |