Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13648884 | 0.74 | CXCR3 (0.55) | L3MBTL1CXCR3 | |
| SCHEMBL7195135 | 0.73 | CXCR3 (0.45) | CXCR3HSD17B10 | |
| Hydrochloric Acid SCHEMBL3976856 | 0.73 | CXCR3 (0.54) | L3MBTL1CXCR3 | |
| Hydrochloric Acid SCHEMBL6821246 | 0.72 | CYP2C9 (0.46) | MEN1KMT2AALDH1A1LMNACXCR3 | |
| SCHEMBL6919706 | 0.72 | CYP2C9 (0.45) | MEN1KMT2AALDH1A1CXCR3KDM4E | |
| SCHEMBL6826032 | 0.71 | P2RY12 (0.49) | TSHRCXCR3 | |
| SCHEMBL5751254 | 0.70 | ALDH1A1 (0.70) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6823744 | 0.69 | KMT2A (0.48) | KMT2AALDH1A1LMNATSHRCXCR3 | |
| SCHEMBL3100293 | 0.67 | FPR2 (0.63) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL6922921 | 0.67 | PLD2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074278-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |