Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821714 | 0.90 | SLC1A3 (0.45) | CASP2GAAKDM4EKMT2ATDP1 | |
| SCHEMBL6717373 | 0.83 | CASP2 (0.45) | CASP2GAAHDAC1KDM4EAPOBEC3A | |
| SCHEMBL6715817 | 0.81 | ALDH1A1 (0.46) | GAAKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL6714265 | 0.80 | KMT2A (0.45) | GAAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL6718599 | 0.76 | CASP2 (0.38) | CASP2GAAHDAC1KDM4EAPOBEC3A | |
| SCHEMBL8348046 | 0.74 | CTSS (0.54) | HDAC1HDAC3HDAC2MAPTHDAC8 | |
| SCHEMBL6824801 | 0.73 | BRD4 (0.60) | KMT2ABRD4MEN1ALDH1A1MAPT | |
| SCHEMBL6717424 | 0.73 | SLC1A3 (0.52) | CASP2GAAHDAC1KDM4EAPOBEC3A | |
| SCHEMBL8348797 | 0.72 | SLC1A3 (0.48) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL6723529 | 0.72 | ALDH1A1 (0.46) | GAAALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |