Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075965 | 0.82 | ATM (0.40) | MEN1KMT2AALDH1A1JAK3BTK | |
| SCHEMBL17075966 | 0.82 | ATM (0.40) | MEN1KMT2AALDH1A1JAK3BTK | |
| SCHEMBL6822106 | 0.81 | CES2 (0.37) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL18222289 | 0.74 | PKM (0.41) | MEN1KMT2A | |
| SCHEMBL18222299 | 0.74 | PKM (0.41) | MEN1KMT2A | |
| SCHEMBL16633285 | 0.72 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL6823139 | 0.71 | CES2 (0.40) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL21526204 | 0.71 | FAAH (0.44) | MEN1KMT2AALDH1A1JAK3BTK | |
| SCHEMBL1126593 | 0.71 | FAAH (0.44) | MEN1KMT2AALDH1A1JAK3BTK | |
| SCHEMBL304799 | 0.71 | CES2 (0.43) | CES2CES1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052363-A1 | OXAZOLIDINONES USED AS ANTIVIRAL AGENTS, IN PARTICULAR FOR FIGHTING AGAINST CYTOMEGALOVIRUS | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | disclosed |