Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822594 | 0.88 | MMP9 (0.48) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL6819234 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL6020216 | 0.83 | CTSK (0.60) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL6020647 | 0.82 | CTSS (0.58) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL6021134 | 0.81 | ATM (0.58) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6021192 | 0.81 | CTSL (0.62) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6461809 | 0.81 | MMP9 (0.50) | CTSSCTSKCTSLMMP9MMP8 | |
| SCHEMBL6021087 | 0.81 | CTSL (0.48) | CTSSCTSKCTSLCTSBMMP9 | |
| SCHEMBL6020580 | 0.80 | CTSL (0.61) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL6020479 | 0.79 | ATM (0.62) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |