Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824647 | 0.92 | KMT2A (0.42) | ALDH1A1MAPTTSHRUSP2RAB9A | |
| SCHEMBL6824040 | 0.89 | NPC1 (0.41) | ALDH1A1MAPTTSHRRAB9AHPGD | |
| SCHEMBL6820561 | 0.87 | UTS2R (0.45) | MEN1KMT2AKCNH2LMNAUTS2R | |
| SCHEMBL6826721 | 0.77 | MEN1 (0.45) | ALDH1A1MAPTTSHRUSP2RAB9A | |
| SCHEMBL6381981 | 0.77 | HTR7 (0.49) | KCNH2UTS2RHTR7 | |
| SCHEMBL6824342 | 0.76 | HTR7 (0.43) | MEN1KMT2AKCNH2UTS2RHTR7 | |
| SCHEMBL6824127 | 0.75 | HTR7 (0.45) | KCNH2UTS2RHTR7 | |
| SCHEMBL7351045 | 0.74 | HTR7 (0.47) | MEN1KMT2AKCNH2UTS2RHTR7 | |
| SCHEMBL6820550 | 0.73 | NPC1 (0.42) | ALDH1A1TSHRRAB9AHPGDMEN1 | |
| SCHEMBL6824089 | 0.73 | HTR7 (0.41) | MEN1KMT2AUTS2RHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |