Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823012 | 0.87 | NPSR1 (0.42) | NPSR1HTTKMT2AF2TPSAB1 | |
| SCHEMBL6823942 | 0.85 | NOS3 (0.46) | HTTKMT2ATPSAB1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6823011 | 0.81 | NPSR1 (0.43) | NPSR1HTTKMT2AF2TPSAB1 | |
| SCHEMBL6823609 | 0.77 | F2 (0.53) | F2PRSS1 | |
| SCHEMBL5103191 | 0.74 | F2 (0.45) | NPSR1F2PRSS1 | |
| SCHEMBL6823784 | 0.72 | NOS3 (0.46) | HTTKMT2ATPSAB1HTR2AHTR2C | |
| SCHEMBL13841233 | 0.68 | MEN1 (0.72) | NPSR1HTTKMT2AF2PRSS1 | |
| SCHEMBL7977518 | 0.68 | KMT2A (0.59) | KMT2ATPSAB1RAB9AGAAMAPT | |
| SCHEMBL28367222 | 0.66 | KMT2A (0.60) | NPSR1KMT2AHPGDRAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL6820134 | 0.66 | NOS3 (0.50) | HTTKMT2ATPSAB1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |