Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823459 | 0.87 | NPSR1 (0.44) | NPSR1HTTF2PRSS1GPR119 | |
| SCHEMBL6823784 | 0.85 | NOS3 (0.46) | HTTMAPTRAB9AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6823011 | 0.82 | NPSR1 (0.43) | NPSR1HTTF2PRSS1GPR119 | |
| SCHEMBL6823609 | 0.77 | F2 (0.53) | F2PRSS1F10 | |
| SCHEMBL6823243 | 0.73 | RAB9A (0.40) | NPSR1HTTMAPTRAB9AALDH1A1 | |
| SCHEMBL6823942 | 0.72 | NOS3 (0.46) | HTTALDH1A1KMT2ATPSAB1 | |
| SCHEMBL28367222 | 0.70 | KMT2A (0.60) | NPSR1MAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL7977518 | 0.69 | KMT2A (0.59) | MAPTRAB9AALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL6820134 | 0.67 | NOS3 (0.50) | HTTMAPTRAB9AALDH1A1POLB | |
| SCHEMBL12133623 | 0.67 | KMT2A (0.76) | NPSR1MAPTRAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |