Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyriprole SCHEMBL29422238 | 0.90 | GABRP (0.41) | IL1BKDM4EALDH1A1KMT2AMEN1 | |
| Pyriprole SCHEMBL27011 | 0.90 | GABRP (0.41) | IL1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL678058 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| Pyriprole SCHEMBL19032727 | 0.82 | GABRP (0.35) | IL1BKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4855148 | 0.82 | GABRP (0.41) | IL1BALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL38664112 | 0.81 | NPC1 (0.36) | IL1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14208660 | 0.80 | GABRP (0.39) | IL1BKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14208642 | 0.80 | GABRP (0.39) | IL1BALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL16118103 | 0.79 | GABRB3 (0.41) | LMNACYP3A4SMN1; SMN2 | |
| SCHEMBL10026162 | 0.76 | NPC1 (0.39) | IL1BALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275583-A1 | Synergistic active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275583-A1 | Synergistic active compound combinations | ACHE, ACAT2, ACAT1 | IL1B 3877/4885KDM4E 3985/4885ALDH1A1 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.