Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.47 |
| ▸ | CDK1 | P06493 | 8/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | CDK9 | P50750 | 4/20 | 0.42 |
| ▸ | CDC7 | O00311 | 3/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826600 | 0.92 | CDK1 (0.53) | CDK2CDK1GSK3BDYRK1ACDK5 | |
| SCHEMBL6824620 | 0.90 | CDK1 (0.49) | CDK2CDK1GSK3BDYRK1ACDK5 | |
| SCHEMBL6915719 | 0.88 | DYRK1A (0.49) | CDK2CDK1GSK3BDYRK1ACDK5 | |
| SCHEMBL6920709 | 0.85 | HSP90AA1 (0.49) | CDK2CDK1GSK3BDYRK1ACDK5 | |
| SCHEMBL7174693 | 0.81 | PRKACA (0.47) | CDK2CDK1GSK3BDYRK1ACDK5 | |
| SCHEMBL7067140 | 0.80 | CDK2 (0.46) | CDK2CDK1GSK3BDYRK1ACDK5 | |
| SCHEMBL6826746 | 0.78 | CDK1 (0.44) | CDK2CDK1GSK3BCDK5CDK5R1 | |
| SCHEMBL6922661 | 0.78 | CDK2 (0.51) | CDK2CDK1GSK3BDYRK1AMAP3K14 | |
| SCHEMBL5803933 | 0.74 | CDK1 (0.58) | CDK2CDK1GSK3BDYRK1AMAP3K14 | |
| SCHEMBL6826566 | 0.74 | CYP2D6 (0.46) | CDK2CDK1JAK2CDC7JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |