Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826600 | 0.80 | CDK1 (0.53) | CDK2CCNT1CCNE1CSNK1A1CSNK1D | |
| SCHEMBL6826746 | 0.78 | CDK1 (0.44) | CDK2CDC7CCNE1CSNK1A1CSNK1D | |
| SCHEMBL6823684 | 0.78 | CDK2 (0.47) | CDK2CDC7CCNT1CSNK2A2CCNE1 | |
| SCHEMBL6824620 | 0.75 | CDK1 (0.49) | CDK2CCNT1CCNE1CSNK1A1CSNK1D | |
| SCHEMBL6915719 | 0.74 | DYRK1A (0.49) | CDK2CDC7CCNT1CCNE1CDK9 | |
| SCHEMBL6917094 | 0.73 | CDK2 (0.42) | CDK2CDC7CCNE1CSNK1A1CSNK1D | |
| SCHEMBL9726804 | 0.72 | MAPT (0.82) | MAPTRAB9ANPC1MAPK1HTT | |
| SCHEMBL7067140 | 0.71 | CDK2 (0.46) | CDK2CDC7CCNT1CCNE1CSNK1A1 | |
| SCHEMBL6920709 | 0.71 | HSP90AA1 (0.49) | CDK2CDC7CCNT1CCNE1CDK9 | |
| SCHEMBL6921150 | 0.70 | CDK1 (0.41) | CDK2CDC7DBF4MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |