Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063772 | 0.89 | HTR7 (0.45) | HTR6HTR7HTR1AHTR1DHTR1B | |
| SCHEMBL6821042 | 0.87 | KDM4E (0.45) | HTR6HTR7HTR1AHTR1DHTR1B | |
| SCHEMBL6922481 | 0.87 | HTR7 (0.49) | HTR6HTR7HTR1BKMT2AMEN1 | |
| SCHEMBL6817332 | 0.86 | HTR6 (0.70) | HTR6HTR7MTNR1AMTNR1BHTR1A | |
| SCHEMBL5768425 | 0.84 | HTR6 (0.74) | HTR6HTR7MTNR1AHTR1ADRD2 | |
| SCHEMBL3561626 | 0.82 | MTNR1A (0.57) | HTR6MTNR1AMTNR1B | |
| SCHEMBL6823922 | 0.80 | CNR1 (0.47) | HTR6KMT2AMEN1PLA2G2A | |
| SCHEMBL6920050 | 0.79 | HTR7 (0.45) | HTR6HTR7HTR1B | |
| SCHEMBL6817324 | 0.77 | HTR6 (0.43) | HTR6HTR7HTR1ADRD2HTR1D | |
| SCHEMBL5101484 | 0.77 | HTR6 (0.53) | HTR6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |