Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676532 | 0.82 | ALDH1A1 (0.32) | ALDH1A1ABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL17491673 | 0.80 | ALOX15 (0.33) | ALDH1A1ABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL28852982 | 0.78 | ALOX15 (0.32) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL3271640 | 0.77 | CYP2C19 (0.33) | ELANEPRKCA | |
| SCHEMBL11153946 | 0.77 | ELANE (0.32) | ELANEPRKCA | |
| SCHEMBL10758697 | 0.77 | ABCB11 (0.33) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL31549892 | 0.77 | PKM (0.31) | PKM | |
| SCHEMBL7710037 | 0.77 | ALDH1A1 (0.41) | ELANEALDH1A1CYP3A4TSHR | |
| SCHEMBL11115592 | 0.77 | — | — | |
| SCHEMBL1141547 | 0.76 | ELANE (0.40) | ELANEALDH1A1PRKCATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| EP-0103265-B1 | BIPHENYLYLPROPIONIC ACID DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-12-03 | — | — | EP | claimed |
| US-4016288-A | ANIMALS, A-HYDRAZINO-3,4-DIHYDROXY-PHENYL-PROPIONIC ACID WITH AN ALANINATE | MERCK & CO., INC. (US) | 1977-04-05 | — | — | US | claimed |
| WO-2004046153-A1 | PRODRUG ESTERS OF CEFTRIAXONE | RANBAXY LABORATORIES LIMITED (IN) | 2004-06-03 | — | — | WO | disclosed |