Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677920 | 0.77 | CYP4F2 (0.42) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL6823924 | 0.77 | ELANE (0.33) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL28204938 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL4676532 | 0.75 | ALDH1A1 (0.32) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL10290185 | 0.75 | — | — | |
| SCHEMBL5613238 | 0.75 | — | — | |
| SCHEMBL31549892 | 0.74 | PKM (0.31) | — | |
| SCHEMBL3948123 | 0.74 | — | — | |
| SCHEMBL14556941 | 0.73 | DGAT1 (0.43) | — | |
| SCHEMBL17491673 | 0.73 | ALOX15 (0.33) | ABCB11CYP1A2CYP3A4TSHRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4681941-A | Method of preparing esters of aryloxyphenoxy propanoic acid | THE DOW CHEMICAL COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0128658-B1 | IMPROVED METHOD OF PREPARING ESTERS OF ARYLOXYPHENOXY PROPANOIC ACID | THE DOW CHEMICAL COMPANY (US) | 1987-06-16 | — | — | EP | disclosed |
| EP-0128658-A1 | Improved method of preparing esters of aryloxyphenoxy propanoic acid | THE DOW CHEMICAL COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |