Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915091 | 0.74 | MEN1 (0.44) | MDM2KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1937570 | 0.73 | MAOA (0.40) | KDM4EATM | |
| SCHEMBL17165118 | 0.68 | IDO1 (0.31) | — | |
| SCHEMBL20585233 | 0.67 | — | — | |
| SCHEMBL5753872 | 0.67 | HRH3 (0.39) | LMNAMAPTSMN1; SMN2KDM4EATM | |
| SCHEMBL11385086 | 0.67 | CHRNB2 (0.54) | — | |
| SCHEMBL31518786 | 0.67 | POLB (0.44) | MDM2KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL2037197 | 0.66 | P2RX7 (0.32) | — | |
| SCHEMBL30569685 | 0.66 | POLB (0.40) | MDM2KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL21176943 | 0.66 | FFAR1 (0.42) | MDM2LMNAMAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046137-A1 | NEW TRICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-06-03 | — | — | WO | disclosed |