Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23183169 | 0.70 | MAPT (0.44) | TRPA1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23022332 | 0.66 | HPGD (0.55) | HPGDUSP2POLBTSHRLMNA | |
| SCHEMBL14940799 | 0.65 | MAPT (0.62) | POLBCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL877703 | 0.64 | ALDH1A1 (0.51) | HPGDPOLBCYP1A2CYP2C9MEN1 | |
| SCHEMBL2527055 | 0.64 | CNR1 (0.50) | HPGDPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15636352 | 0.64 | MAPT (0.45) | TSHRLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL720894 | 0.64 | GABRP (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19651818 | 0.63 | KMT2A (0.56) | HPGDUSP2POLBTSHRLMNA | |
| SCHEMBL5697696 | 0.63 | LMNA (0.52) | HPGDPOLBTSHRLMNAKMT2A | |
| Fluoride SCHEMBL3339659 | 0.62 | GABRP (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074278-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |