SCHEMBL349574

SCHEMBL349574

CC(=O)N(C)C.COC(C)OC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylcarbate SCHEMBL6824434 0.83 SLC1A3 (0.32) TSHRALDH1A1CHRNB2CHRNA4
SCHEMBL5589932 0.83 ALDH1A1 (0.34) TSHRALDH1A1CHRNB2CHRNA4CHRM2
Acetone SCHEMBL593191 0.82 LMNA (0.43) TSHRALDH1A1
SCHEMBL28324219 0.80 ALDH1A1 (0.35) TSHRALDH1A1
Acetic Acid SCHEMBL10711426 0.79 FFAR3 (0.47) TSHRALDH1A1
SCHEMBL10829544 0.79 CHRM1 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
Acetamide SCHEMBL11118916 0.77 LMNA (0.50) TSHRALDH1A1CHRM2CHRM4CHRM5
Isopropyl Alcohol SCHEMBL22551253 0.76 ALDH1A1 (0.43) TSHRALDH1A1CHRNB2CHRNA4CHRM2
Bicarbonate SCHEMBL6258274 0.76 TP53 (0.39) TSHRALDH1A1
SCHEMBL7993349 0.75 HTR1A (0.36) ALDH1A1CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105418635-A Synthesis method of thienopyridine medical intermediate SHANGHAI INST TECHNOLOGY 2016-03-23 CN claimed
CN-103935987-B A kind of CO 2the preparation method of responsiveness functional graphene oxide TONGJI UNIVERSITY (CN) 2015-10-21 CN claimed
CN-103935987-A CO2-responsive functionalized graphene oxide preparation method UNIV TONGJI 2014-07-23 CN claimed
CN-101891758-A Method for synthesizing 7-imethylamino-2, 2-dimethyl-6-ene-3, 5-suberaldehyde-O, O-boron difluoride BEIJING AGLAIA TECHNOLOGY & DEV CO LTD 2010-11-24 CN claimed
CN-101891725-A 2-methyl-6-tert-butyl-4-dicyanmethylene-4H-pyran synthesis method BEIJING AGLAIA TECHNOLOGY & DEV CO LTD 2010-11-24 CN claimed
CN-100420697-C Method of preparing trichloro sucrose-6-organic acid ester HEBEI SUKERUI SCI & TECH CO LT (CN) 2008-09-24 CN claimed
CN-1948326-A Method of preparing trichloro sucrose-6-organic acid ester HEBEI SUKERUI SCI & TECH CO LT (CN) 2007-04-18 CN claimed
US-20260138978-A1 POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 VANDERBILT UNIV (US) 2026-05-21 US disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER SHOFU INC (JP) 2025-02-27 US disclosed
EP-4473954-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER Shofu Inc. (JP) 2024-12-11 EP disclosed
US-20240360084-A1 PYRAZOLE AND IMIDAZOLE COMPOUNDS FOR INHIBITION OF IL-17 AND RORGAMMA REATA PHARMACEUTICALS INC (US) 2024-10-31 US disclosed
EP-3800186-B1 CYANOPYRROLIDINES AS DUB INHIBITORS FOR THE TREATMENT OF CANCER MISSION THERAPEUTICS LTD (GB) 2024-10-02 EP disclosed
US-4246409-A ANTIDIARRHEAL AGENTS WILLIAM H. RORER, INC. (US) 1981-01-20 US disclosed
EP-0016277-A1 2-Carbonyl-3-hydroxy-alkenonitriles, their use as anti-arthritic agents and processes for their preparation AMERICAN CYANAMID COMPANY (US) 1980-10-01 EP disclosed
US-4225315-A Triazinones from amidinoureas WILLIAM H. RORER, INC. (US) 1980-09-30 US disclosed
WO-1980000964-A1 ANTI-INFLAMMATORY AGENTS INCLUDING 2-CARBONYL-3-HYDROXY-2-ALKENONITRILES AMERICAN CYANAMID CO (US) 1980-05-15 WO disclosed
US-4197310-A ANTIARTHRITIC, ANTIINFLAMMATORY, PREVENT JOINT DETERIORATION AMERICAN CYANAMID COMPANY (US) 1980-04-08 US disclosed
US-4181677-A ANTIINFLAMMATORY AGENTS AMERICAN CYANAMID COMPANY (US) 1980-01-01 US disclosed
US-4173650-A ANTIARTHRITIC AGENTS AMERICAN CYANAMID COMPANY (US) 1979-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 TSHR 3276/4885ALDH1A1 314/4885CHRNB2 2014/4885
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER ERCC1, DSC1, CRYAA TSHR 4039/4885ALDH1A1 479/4885CHRNB2 3355/4885
US-20240360084-A1 PYRAZOLE AND IMIDAZOLE COMPOUNDS FOR INHIBITION OF IL-17 AND RORGAMMA RORC, RORB, RORA TSHR 1233/4885ALDH1A1 672/4885CHRNB2 3230/4885
US-20260138978-A1 POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 CHRM1, CHRM4, CHRM2 TSHR 120/4885ALDH1A1 1029/4885CHRNB2 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.