Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825654 | 0.87 | KDM4E (0.62) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL6825118 | 0.81 | KDM4E (0.55) | ALDH1A1HPGDKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL6919910 | 0.80 | MAPK14 (0.51) | ALDH1A1HPGDMEN1KMT2ACSF1R | |
| SCHEMBL6824640 | 0.76 | KDM4E (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL6825083 | 0.76 | GRIN2D (0.41) | ALDH1A1HPGDMEN1KMT2ACSF1R | |
| SCHEMBL6825043 | 0.72 | KDM4E (0.47) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL7040419 | 0.72 | PTGS2 (0.52) | ALDH1A1HPGDKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL24095578 | 0.71 | MEN1 (0.59) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL14796348 | 0.71 | KDM4E (0.45) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL6976263 | 0.71 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089930-A1 | 4-FLUOROQUINOLONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | IMCLONE SYSTEMS INCORPORATED (US) | 2004-10-21 | — | — | WO | disclosed |