Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898638 | 0.80 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL28626450 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL21494388 | 0.77 | ADRA2A (0.47) | SLC6A2SLC6A4SLC6A3KDM4ECYP1A2 | |
| SCHEMBL11191009 | 0.77 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL4611560 | 0.77 | PPARA (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL21881598 | 0.77 | PPARA (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL11001241 | 0.76 | SMN1; SMN2 (0.41) | KDM4ECYP1A2ALDH1A1LMNAPOLB | |
| SCHEMBL8787698 | 0.74 | CYP2D6 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6KDM4E | |
| SCHEMBL5521719 | 0.73 | LMNA (0.44) | CYP2D6KDM4ECYP1A2ALDH1A1LMNA | |
| SCHEMBL6965784 | 0.73 | NOS2 (0.45) | SLC6A2SLC6A4SLC6A3CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087667-A1 | ESTER DERIVATIVES OF (PYRIDINYLOXY-PHENYL)-METHANOL AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | claimed |
| WO-2004087667-A1 | ESTER DERIVATIVES OF (PYRIDINYLOXY-PHENYL)-METHANOL AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087667-A1 | ESTER DERIVATIVES OF (PYRIDINYLOXY-PHENYL)-METHANOL AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | disclosed |