Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716864 | 0.82 | PGR (0.47) | POLBPGRSCN1ASCN2ASCN3A | |
| SCHEMBL8347137 | 0.74 | CTSS (0.46) | POLBPGRSCN1ASCN2ASCN3A | |
| SCHEMBL6716729 | 0.71 | PGR (0.45) | PGRSCN1ASCN2ASCN3AMAPT | |
| SCHEMBL6825277 | 0.69 | CYP1A2 (0.49) | POLBPGRSCN1ASCN2ASCN3A | |
| SCHEMBL6723698 | 0.69 | KMT2A (0.47) | POLBPGRSCN1ASCN2ASCN3A | |
| SCHEMBL28905936 | 0.69 | ALOX5 (0.58) | ALDH1A1HSD17B10ALOX5TSHR | |
| SCHEMBL28905939 | 0.69 | ALOX5 (0.58) | ALDH1A1HSD17B10ALOX5TSHR | |
| SCHEMBL28905959 | 0.69 | ALOX5 (0.58) | ALDH1A1HSD17B10ALOX5TSHR | |
| SCHEMBL6824933 | 0.68 | POLB (0.41) | POLBPGRSCN1ASCN2ASCN3A | |
| SCHEMBL13626442 | 0.68 | HPGD (0.65) | POLBMAPTLMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |