Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946681 | 0.71 | RAB9A (0.56) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL918766 | 0.70 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6824977 | 0.69 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11509919 | 0.69 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL16688479 | 0.69 | CSNK2A2 (0.72) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6824627 | 0.68 | CHRNB2 (0.51) | MEN1KMT2AMAPTCYP1A2PKM | |
| SCHEMBL10930595 | 0.68 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4293350 | 0.68 | RAB9A (0.77) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL5401761 | 0.67 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL995829 | 0.67 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | disclosed |