SCHEMBL3660974

SCHEMBL3660974

CC(C)C[C@H](N)C(=O)N(C(=O)OCc1ccccc1)[C@@H](Cc1ccccc1)B(O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.44
RNPEP Q9H4A4 1/20 0.44
DNPEP Q9ULA0 1/20 0.44
PSMB5 P28074 3/20 0.43
PSMB11 A5LHX3 1/20 0.42
PSMA7 O14818 1/20 0.42
PSMB1 P20618 1/20 0.42
PSMA1 P25786 1/20 0.42
PSMA2 P25787 1/20 0.42
PSMA3 P25788 1/20 0.42
PSMA4 P25789 1/20 0.42
PSMB8 P28062 1/20 0.42
PSMB9 P28065 1/20 0.42
PSMA5 P28066 1/20 0.42
PSMB4 P28070 1/20 0.42
PSMB6 P28072 1/20 0.42
PSMB10 P40306 1/20 0.42
PSMB3 P49720 1/20 0.42
PSMB2 P49721 1/20 0.42
PSMA6 P60900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3666751 0.89 CTSK (0.40) ANPEPRNPEPDNPEPPSMB5PSMB11
SCHEMBL9023544 0.86 SLC15A1 (0.45) PSMB5PSMB11PSMA7PSMB1PSMA1
SCHEMBL27809385 0.84 ANPEP (0.48) ANPEPRNPEPDNPEPCTSBSLC15A1
SCHEMBL8586811 0.82 CTSB (0.47) ANPEPRNPEPDNPEPPSMB5PSMB1
SCHEMBL7420644 0.81 ANPEP (0.43) ANPEPRNPEPDNPEPCTSBSLC15A1
SCHEMBL10443784 0.80 SLC15A1 (0.46) ANPEPRNPEPDNPEPCTSBSLC15A1
SCHEMBL724023 0.80 CTSK (0.44) ANPEPRNPEPDNPEPCTSBSLC15A1
SCHEMBL1014662 0.80 CTSB (0.44) ANPEPRNPEPDNPEPPSMB5PSMB1
SCHEMBL6825539 0.79 ANPEP (0.43) ANPEPRNPEPDNPEPCTSBSLC15A1
SCHEMBL8584909 0.79 CTSB (0.44) ANPEPRNPEPDNPEPCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2234600-A1 ANTIBODY FORMULATION F. Hoffmann-La Roche AG (CH) 2010-10-06 EP disclosed
WO-2009080541-A1 ANTIBODY FORMULATION F. HOFFMANN-LA ROCHE AG (CH) 2009-07-02 WO disclosed