Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825995 | 0.81 | DRD4 (0.33) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6820130 | 0.79 | SYK (0.38) | SYKKDM4EALDH1A1SMN1; SMN2AURKB | |
| SCHEMBL6820484 | 0.78 | SYK (0.39) | SYKKDM4EALDH1A1SMN1; SMN2AURKB | |
| SCHEMBL6826220 | 0.75 | RAB9A (0.37) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6826385 | 0.69 | SIGMAR1 (0.43) | KDM4EALDH1A1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL8472048 | 0.66 | SMN1; SMN2 (0.49) | SYKKDM4EALDH1A1SMN1; SMN2PARP10 | |
| SCHEMBL14075065 | 0.66 | SMN1; SMN2 (0.45) | SYKKDM4EALDH1A1SMN1; SMN2AURKB | |
| SCHEMBL15865998 | 0.65 | SMN1; SMN2 (0.46) | SYKKDM4EALDH1A1SMN1; SMN2AURKB | |
| SCHEMBL15865983 | 0.65 | ALDH1A1 (0.45) | SYKKDM4EALDH1A1SMN1; SMN2AURKB | |
| Hydrochloric Acid SCHEMBL27463197 | 0.65 | SMN1; SMN2 (0.44) | SYKKDM4EALDH1A1SMN1; SMN2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099185-A1 | 2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |