Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826371 | 0.79 | ALDH1A1 (0.39) | RAB9ANPC1SMN1; SMN2POLBGAA | |
| SCHEMBL6825967 | 0.75 | SYK (0.37) | RAB9ASMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL7268161 | 0.71 | GAA (0.45) | RAB9ANPC1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL12164511 | 0.70 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL6826385 | 0.68 | SIGMAR1 (0.43) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL6820130 | 0.68 | SYK (0.38) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL6701202 | 0.67 | CYP3A4 (0.50) | SMN1; SMN2CYP1A2GPR119RETKMT2A | |
| SCHEMBL4678395 | 0.67 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL29611056 | 0.67 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL4923232 | 0.67 | AKT1 (0.46) | RAB9ANPC1GPR119GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099185-A1 | 2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |