Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828922 | 0.93 | SCN10A (0.48) | SCN10APTPN11ALDH1A1KDM4EPDE4B | |
| SCHEMBL6829403 | 0.89 | SCN10A (0.63) | SCN10APTPN11ALDH1A1KDM4EKIF18A | |
| SCHEMBL6825969 | 0.86 | SCN10A (0.52) | SCN10AALDH1A1KDM4EKIF18A | |
| SCHEMBL6831083 | 0.84 | SCN10A (0.51) | SCN10APTPN11KIF18A | |
| SCHEMBL6647476 | 0.77 | SCN10A (0.46) | SCN10APTPN11ALDH1A1KDM4EHPGD | |
| SCHEMBL6645593 | 0.76 | MAPT (0.48) | SCN10APTPN11ALDH1A1KDM4ETSHR | |
| SCHEMBL6644850 | 0.76 | PTPN11 (0.42) | SCN10APTPN11ALDH1A1KDM4EKIF18A | |
| SCHEMBL6643110 | 0.73 | PTPN11 (0.41) | SCN10APTPN11ALDH1A1KDM4EKIF18A | |
| SCHEMBL6830991 | 0.73 | SCN10A (0.48) | SCN10AALDH1A1KDM4EKIF18A | |
| SCHEMBL6829260 | 0.72 | SCN10A (0.63) | SCN10AKIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |