Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828987 | 0.93 | SCN10A (0.52) | SCN10APTPN11PDE4BKIF18AALDH1A1 | |
| SCHEMBL6829403 | 0.84 | SCN10A (0.63) | SCN10APTPN11KIF18AMAPTALDH1A1 | |
| SCHEMBL6825969 | 0.81 | SCN10A (0.52) | SCN10AKIF18AMAPTALDH1A1KDM4E | |
| SCHEMBL6831083 | 0.78 | SCN10A (0.51) | SCN10APTPN11KIF18A | |
| SCHEMBL6646240 | 0.77 | RAB9A (0.39) | SCN10APTPN11MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6645260 | 0.74 | PTPN11 (0.38) | SCN10APTPN11KIF18AALDH1A1KDM4E | |
| SCHEMBL6647476 | 0.71 | SCN10A (0.46) | SCN10APTPN11KIF18AALDH1A1KDM4E | |
| SCHEMBL6644850 | 0.70 | PTPN11 (0.42) | SCN10APTPN11KIF18AALDH1A1KDM4E | |
| SCHEMBL6645593 | 0.70 | MAPT (0.48) | SCN10APTPN11MAPTALDH1A1KDM4E | |
| SCHEMBL6829509 | 0.70 | L3MBTL1 (0.40) | SCN10AMAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |