Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 17/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 17/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826137 | 0.83 | TMPRSS15 (0.41) | PRSS1TMPRSS15 | |
| SCHEMBL6925215 | 0.78 | PRSS1 (0.40) | PRSS1TMPRSS15 | |
| SCHEMBL6828754 | 0.76 | KMT2A (0.42) | PRSS1TMPRSS15 | |
| SCHEMBL6831000 | 0.73 | BCHE (0.43) | PRSS1TMPRSS15 | |
| SCHEMBL6828740 | 0.73 | MAPT (0.41) | PRSS1TMPRSS15 | |
| SCHEMBL6829229 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL6826412 | 0.71 | SMN1; SMN2 (0.44) | PRSS1TMPRSS15 | |
| SCHEMBL2226671 | 0.71 | NPSR1 (0.53) | ERN1 | |
| SCHEMBL6826417 | 0.71 | MRGPRX4 (0.35) | PRSS1TMPRSS15ERN1 | |
| SCHEMBL2653044 | 0.70 | HDAC3 (0.55) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |