Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828740 | 0.84 | MAPT (0.41) | KMT2APOLBPRSS1TMPRSS15MEN1 | |
| SCHEMBL6828835 | 0.84 | LMNA (0.44) | KMT2ATDP1ATMPRSS1TMPRSS15 | |
| SCHEMBL6829094 | 0.84 | PRSS1 (0.42) | KMT2APOLBPRSS1TMPRSS15MEN1 | |
| SCHEMBL6829103 | 0.84 | KIF11 (0.44) | KMT2APRSS1TMPRSS15ALDH1A1MAPT | |
| SCHEMBL6831170 | 0.81 | MAPT (0.50) | KMT2ATDP1PRSS1TMPRSS15MEN1 | |
| SCHEMBL6826137 | 0.80 | TMPRSS15 (0.41) | POLBTDP1PRSS1TMPRSS15KDM4E | |
| SCHEMBL6826064 | 0.78 | CHRNA3 (0.39) | KMT2APRSS1TMPRSS15MEN1ALDH1A1 | |
| SCHEMBL6925215 | 0.77 | PRSS1 (0.40) | KMT2APRSS1TMPRSS15MEN1RAB9A | |
| SCHEMBL6826110 | 0.76 | PRSS1 (0.35) | PRSS1TMPRSS15 | |
| SCHEMBL12644603 | 0.76 | TTR (0.61) | TTRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |