Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828740 | 0.79 | MAPT (0.41) | MAPTKMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL6826064 | 0.78 | CHRNA3 (0.39) | MAPTKMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL6925215 | 0.75 | PRSS1 (0.40) | MRGPRX4KMT2ANPC1HPGDRAB9A | |
| SCHEMBL2226671 | 0.71 | NPSR1 (0.53) | MRGPRX4MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6826110 | 0.71 | PRSS1 (0.35) | ERN1PRSS1TMPRSS15 | |
| SCHEMBL6828835 | 0.70 | LMNA (0.44) | MAPTKMT2ASMN1; SMN2NPC1HPGD | |
| SCHEMBL6829094 | 0.70 | PRSS1 (0.42) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6828754 | 0.70 | KMT2A (0.42) | MAPTKMT2ASMN1; SMN2NPC1GAA | |
| SCHEMBL6826137 | 0.69 | TMPRSS15 (0.41) | TDP1NPSR1PRSS1TMPRSS15KDM4E | |
| SCHEMBL6831122 | 0.69 | LMNA (0.50) | MAPTKMT2ANPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |