Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826137 | 0.86 | TMPRSS15 (0.41) | PRSS1TMPRSS15L3MBTL1MAPK1 | |
| SCHEMBL6826110 | 0.78 | PRSS1 (0.35) | PRSS1TMPRSS15 | |
| SCHEMBL6828754 | 0.77 | KMT2A (0.42) | PRSS1TMPRSS15RAB9ANPC1HPGD | |
| SCHEMBL6826064 | 0.77 | CHRNA3 (0.39) | PRSS1TMPRSS15RAB9ANPC1HPGD | |
| SCHEMBL6826417 | 0.75 | MRGPRX4 (0.35) | PRSS1TMPRSS15RAB9ANPC1MRGPRX4 | |
| SCHEMBL6826412 | 0.73 | SMN1; SMN2 (0.44) | PRSS1TMPRSS15KMT2A | |
| SCHEMBL6831000 | 0.72 | BCHE (0.43) | PRSS1TMPRSS15HPGDKMT2AMEN1 | |
| SCHEMBL6921975 | 0.72 | RAB9A (0.38) | RAB9ANPC1HPGDKMT2AMEN1 | |
| SCHEMBL6828740 | 0.72 | MAPT (0.41) | PRSS1TMPRSS15RAB9ANPC1HPGD | |
| SCHEMBL8759715 | 0.71 | RAB9A (0.46) | RAB9ANPC1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |