Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831024 | 0.83 | TERT (0.60) | TERTALDH1A1MAPTNPC1LMNA | |
| SCHEMBL6830047 | 0.83 | MAPT (0.41) | TERTMGAMGAASIMGAM2 | |
| SCHEMBL6831124 | 0.80 | TERT (0.51) | TERTMGAMGAASIMGAM2 | |
| SCHEMBL6826142 | 0.80 | TERT (0.51) | TERTMGAMGAASIMGAM2 | |
| SCHEMBL6828953 | 0.80 | TERT (0.51) | TERTALDH1A1MAPTLMNATSHR | |
| SCHEMBL6831061 | 0.79 | MAPT (0.51) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL29183765 | 0.79 | MAPT (0.50) | GAAALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL7121858 | 0.75 | ALDH1A1 (0.66) | GAAALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL6826130 | 0.74 | KMT2A (0.41) | GAAALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL7872708 | 0.74 | ALDH1A1 (0.51) | TERTGAAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |