Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PNP | P00491 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42313 | 0.78 | ADORA2A (0.42) | ALDH1A1HPGDSMN1; SMN2USP2TP53 | |
| SCHEMBL6831168 | 0.75 | CSNK2A2 (0.41) | ALDH1A1HPGDSMN1; SMN2USP2TP53 | |
| SCHEMBL6829678 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2USP2TP53 | |
| SCHEMBL11125305 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2USP2TP53 | |
| SCHEMBL12489702 | 0.75 | CHEK1 (0.36) | ALDH1A1HPGDSMN1; SMN2USP2TP53 | |
| SCHEMBL6826187 | 0.73 | NUDT1 (0.44) | ALDH1A1HPGDXDHKDM4EHSD17B10 | |
| SCHEMBL20460318 | 0.72 | JAK3 (0.49) | ALDH1A1HPGDSMN1; SMN2TP53ADORA3 | |
| SCHEMBL843216 | 0.67 | ADORA2A (0.40) | ADORA3XDHLMNANUDT1ADORA2A | |
| SCHEMBL264364 | 0.65 | PI4KA (0.33) | ALDH1A1HPGDSMN1; SMN2TP53PTGS1 | |
| SCHEMBL10518128 | 0.64 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2USP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214198-A1 | Allele-targeted RNA interference | UNIVERSITY OF MASSACHUSETTS | 2004-10-28 | — | — | US | disclosed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | disclosed |