SCHEMBL264364

SCHEMBL264364

Fc1ncnc2[nH]cnc12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.33
PI4K2B Q8TCG2 2/20 0.33
PI4K2A Q9BTU6 2/20 0.33
PI4KB Q9UBF8 2/20 0.33
LMNA P02545 1/20 0.33
DRD3 P35462 1/20 0.33
XDH P47989 1/20 0.33
LRRK2 Q5S007 1/20 0.33
PARP1 P09874 1/20 0.32
MKNK1 Q9BUB5 1/20 0.32
CSNK2A2 P19784 2/20 0.31
CSNK2A1 P68400 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
PTGS1 P23219 1/20 0.31
HBB P68871 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL3416954 0.74 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL3413247 0.74 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL10285464 0.74 PI4KA (0.34) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL3414603 0.74 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL8110 0.74 PI4KA (0.48) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL129804 0.73 PDPK1 (0.37) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL5601016 0.73 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL691914 0.73 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBLMNA
Adenine SCHEMBL20485928 0.73 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL13014 0.73 CSNK2A2 (0.40) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717779-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TriLink BioTechnologies, LLC (US) 2026-04-01 EP claimed
US-7265111-B2 Adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-09-04 US claimed
EP-1527083-A1 NOVEL ADENOSINE ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS Aventis Pharma Deutschland GmbH (DE) 2005-05-04 EP claimed
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-07-01 US claimed
WO-2004003002-A1 NOVEL ADENOSINE ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-01-08 WO claimed
EP-1375508-A1 N6-substituted adenosine analogues and their use as pharmaceutical agents Aventis Pharma Deutschland GmbH (DE) 2004-01-02 EP claimed
CN-1117870-C Method for producing nucleoside-5' -phosphate ester AJINOMOTO KK (JP) 2003-08-13 CN claimed
US-5817799-A 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-10-06 US claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
JP-3076594-A None JP disclosed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US disclosed
EP-4717779-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TriLink BioTechnologies, LLC (US) 2026-04-01 EP disclosed
EP-4276189-B1 INITIATING CAPPED OLIGONUCLEOTIDE PRIMERS FOR SYNTHESIZING 5'-CAPPED RNAS TRILINK BIOTECHNOLOGIES LLC (US) 2026-04-01 EP disclosed
EP-0463999-A1 Improvements in or relating to organic compounds SANDOZ LTD. (CH) 1992-01-02 EP disclosed
WO-1991012260-A1 6-HALO- AND 2-AMINO-6-HALO-PURINE 2',3'-DIDEOXY NUCLEOSIDES AND THEIR USE AS ANTIVIRAL AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1991-08-22 WO disclosed
JP-H0376594-A PRODUCTION OF DIDEOXYNUCLEOTIDE DERIVATIVE AJINOMOTO CO INC 1991-04-02 JP disclosed
JP-H00376594-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION RNGTT, RNMT, UPF1 PI4KA 4241/4885PI4K2B 3370/4885PI4K2A 3707/4885
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents ADORA1, ADORA2A, ADORA2B PI4KA 845/4885PI4K2B 504/4885PI4K2A 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.