Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389566 | 0.78 | GAA (0.50) | GAAKDM4EALDH1A1ALOX15CYP3A4 | |
| SCHEMBL4678395 | 0.76 | SMN1; SMN2 (0.61) | GAAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL29611056 | 0.76 | SMN1; SMN2 (0.61) | GAAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL30992257 | 0.75 | SMN1; SMN2 (0.59) | GAAKDM4EALDH1A1ALOX15KMT2A | |
| SCHEMBL14074323 | 0.73 | GAA (0.43) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14074324 | 0.71 | TRPV3 (0.37) | KDM4ECYP3A4 | |
| SCHEMBL6826220 | 0.71 | RAB9A (0.37) | GAAKDM4EALDH1A1ALOX15KMT2A | |
| SCHEMBL2390889 | 0.71 | AKT1 (0.42) | GAAKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19185892 | 0.71 | CA12 (0.48) | GAACYP3A4KMT2AMEN1RECQL | |
| SCHEMBL4066257 | 0.70 | KMT2A (0.46) | ALDH1A1CYP3A4KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018046-A1 | Chemokine receptor binding heterocyclic compounds | GENZYME CORPORATION | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018046-A1 | Chemokine receptor binding heterocyclic compounds | CXCR3, ACKR3, CCR2 | GAA 4680/4885KDM4E 4709/4885ALDH1A1 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.