Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826409 | 0.84 | DAO (0.38) | MAPTALDH1A1POLBL3MBTL1RECQL | |
| SCHEMBL6829495 | 0.82 | MAOA (0.43) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL510175 | 0.76 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6829742 | 0.75 | MAPT (0.40) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6825954 | 0.70 | L3MBTL1 (0.51) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL158329 | 0.69 | — | — | |
| SCHEMBL29020313 | 0.68 | ALDH1A1 (0.44) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL20704671 | 0.68 | CYP2A6 (0.57) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6924355 | 0.68 | ALDH1A1 (0.47) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1680586 | 0.67 | PRMT6 (0.47) | MAPTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |