Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826432 | 0.84 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1LMNARECQL | |
| SCHEMBL1680352 | 0.76 | ALOX5 (0.42) | ADRA1DADRA1AADRA1BMAPTSMN1; SMN2 | |
| SCHEMBL6829495 | 0.73 | MAOA (0.43) | DAOMAOAMAOBADRA1DADRA1A | |
| SCHEMBL7126366 | 0.71 | L3MBTL1 (0.43) | DAOMAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL30762026 | 0.69 | — | — | |
| SCHEMBL7129657 | 0.69 | ALDH1A1 (0.48) | MAPTSMN1; SMN2ALDH1A1LMNARECQL | |
| SCHEMBL6829742 | 0.69 | MAPT (0.40) | ADRA1DADRA1AADRA1BMAPTSMN1; SMN2 | |
| SCHEMBL29020313 | 0.68 | ALDH1A1 (0.44) | ADRA1DADRA1AADRA1BMAPTALDH1A1 | |
| SCHEMBL6829718 | 0.67 | TERT (0.47) | DAOMAPTALDH1A1HPGDNPC1 | |
| SCHEMBL30762031 | 0.66 | ALDH1A1 (0.39) | ADRA1DADRA1AADRA1BALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |