Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828650 | 0.86 | KDM4E (0.43) | RAB9AKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL6829309 | 0.79 | KMT2A (0.49) | KMT2AL3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL6826474 | 0.78 | ALDH1A1 (0.41) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6829332 | 0.76 | ALDH1A1 (0.39) | RAB9ANPC1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6829499 | 0.74 | ALDH1A1 (0.41) | RAB9ANPC1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6830993 | 0.73 | TERT (0.48) | L3MBTL1ALDH1A1CYP1A2ALOX15MAPT | |
| SCHEMBL6826069 | 0.73 | KMT2A (0.47) | KMT2AL3MBTL1MEN1ALDH1A1KDM4E | |
| SCHEMBL6829312 | 0.73 | TDP1 (0.44) | RAB9ANPC1KMT2AL3MBTL1MEN1 | |
| SCHEMBL6828651 | 0.73 | PRSS1 (0.45) | RAB9ANPC1KMT2AL3MBTL1MEN1 | |
| SCHEMBL8759715 | 0.72 | RAB9A (0.46) | RAB9ANPC1KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |