Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.53 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826804 | 0.78 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947125 | 0.77 | HTR6 (0.65) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6829943 | 0.77 | HTR6 (0.46) | HTR6AVPR1BCYP3A4CYP2D6HRH4 | |
| SCHEMBL14732435 | 0.71 | FABP3 (0.58) | HTR6 | |
| SCHEMBL6829294 | 0.69 | HTR6 (0.50) | HTR6CYP3A4CYP2D6KMT2AHRH4 | |
| SCHEMBL3087652 | 0.68 | POLB (0.59) | HTR6CYP3A4CYP2D6KMT2APOLB | |
| SCHEMBL3556363 | 0.68 | HTR6 (0.49) | HTR6 | |
| SCHEMBL6826369 | 0.68 | HTR6 (0.55) | HTR6CYP3A4CYP2D6KMT2A | |
| SCHEMBL27933235 | 0.66 | HTR6 (0.45) | HTR6 | |
| SCHEMBL6829313 | 0.66 | DRD2 (0.48) | HTR6AVPR1BCYP3A4CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |