Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700606 | 0.72 | CLPP (0.38) | — | |
| SCHEMBL6288793 | 0.70 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL6292115 | 0.69 | MMP13 (0.36) | — | |
| SCHEMBL6288773 | 0.68 | S1PR1 (0.44) | — | |
| SCHEMBL6703987 | 0.67 | CLPP (0.37) | — | |
| SCHEMBL6702169 | 0.65 | MMP13 (0.41) | LMNAMAPT | |
| SCHEMBL6698925 | 0.65 | MAPK1 (0.35) | — | |
| SCHEMBL6700135 | 0.64 | MAPK1 (0.35) | — | |
| SCHEMBL6289365 | 0.63 | ADRA1A (0.34) | — | |
| SCHEMBL6704262 | 0.62 | P2RX7 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014375-A2 | FUSED BICYCLIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |